Post-doctoral scientist - Functional Genomics

Company: Center for Watershed Protection
Location: Cleveland
Posted on: April 10, 2021

Job Description:

Post-doctoral scientist - Functional Genomics Case Western Reserve University Application Attachments: Please include your resume and up to two additional documents. Add File Department of Genetics and Genome Sciences Case Western Reserve University Cleveland, Ohio. USA Regulatory interactions of ETS transcription factors. Our goal is to determine the mechanisms of cross-talk between the epithelial-selective ETS-family transcription factors EHF and ELF5. These factors are encoded by neighboring genes located at the cystic fibrosis (CF) modifier region on chr11p13, which is associated with CF lung disease severity. EHF and ELF5 are candidate targets of the disease-associated SNPs within the non-coding regions of the modifier region. Both factors have pivotal roles in maintaining epithelial integrity and regulate multiple processes relevant to lung disease (Swahn et al., J. Cell. Mol. Med. 2019 23:7726-7740; Fossum et al., 2017-- J. Biol. Chem. 292:10938-10949 ). Successful applicants will have a strong record of accomplishment as shown by publications as a graduate student and/or postdoc, be highly motivated, and have a passion for elucidating disease mechanisms by functional genomics approaches. Expertise in one or more of the following areas is required: transcription factor biology/biochemistry; post-translational modifications; cell biology; genomics technologies including ATAC-seq, ChIP-seq, cut&run, RNA-seq and the use of relevant bioinformatic pipelines. Familiarity with general techniques of molecular biology and mammalian cell biology is essential. We are part of a vibrant and interactive research community at Case Western Reserve University and occupy excellent, modern laboratory space. Please send an electronic letter of application, quoting the reference CWRU/AH2/2021, Curriculum Vitae and contact information of 3 referees to: jobsview@case.edu. Hiring is contingent upon eligibility to work in the United States. DIVERSITY STATEMENT: In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply. REASONABLE ACCOMMODATIONS: Case Western Reserve University provides reasonable accommodations to applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Inclusion, Diversity and Equal Opportunity at 216-368-8877 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis. NOTES:
Additional Salary Information: Salary based upon years of experience.
Internal Number: CWRU/AH2/2021 About Case Western Reserve University Case Western Reserve University (CWRU): CWRU, a private research-intensive university in Cleveland, Ohio, was created in 1967 by the federation of the Case Institute of Technology (founded in 1881) and Western Reserve University (founded in 1826). Its mission is to improve people's lives through research and education. CWRU has eight comprehensive schools: Engineering; Arts and Sciences; Applied Social Sciences; Dental Medicine; Law; Medicine; Nursing; and Management. The current student population is > 11,000 (49% male and 51% female) consisting of -5,150 undergraduate, -2,600 graduate students and -3,900 professional students. The excess of graduate and professional students is testament to the school's dedication to advanced training and research. International students represent 19% of the total student population. Approximately 11% self-identify as African American, Native American, Hawaiian, or Hispanic, or mixed-race/ethnicity, and 15% are of Asian descentSchool of Medicine (SOM): The School of Medicine (SOM) has a long, rich history as one of the top medical schools and research-intensive institutions in the country. Since its founding in 1843, the SOM has been ... Show more Center for Advanced Bioenergy and Bioproducts Innovation (CABBI) 1 Week Ago BACK TO TOP Powered By Become a Member Join a national network of professionals dedicated to advancing the state-of-the-art in watershed and stormwater management, and receive exclusive benefits and discounts.

Keywords: Center for Watershed Protection, Cleveland , Post-doctoral scientist - Functional Genomics, Other , Cleveland, Ohio