Senior Research Assistant
Company: Case Western Reserve University
Posted on: September 20, 2023
Working with a high degree of independence and under general
direction of the laboratory manager, coordinate major activities in
research and diagnostic related technical areas. The Research
Assistant 4 will assist in coordination of major activities for the
chemistry subdiscipline, using a variety of analytic platforms for
diagnostic testing and research efforts at the National Prion
Disease Pathology Surveillance Center. In addition, cross train and
acquire proficiency in other protein-based testing, including
molecular testing for research and diagnostics.
- Provide input and recommendation to principal investigator and
laboratory director regarding significant developments in research
projects, new test validation for diagnostic, and surveillance
monitoring. Coordinate all major diagnostic testing activities and
research in the lab. This includes maintaining schedules, ensuring
compliance with protocol guidelines and requirements of regulatory
agencies; identifying problems and/or inconsistencies and monitor
study participants' progress to include documentation and reporting
of adverse events; recommend corrective action as appropriate.
Prepare IRB updates. Represent the lab and serve as a liaison
between study sponsors, clinical research organizations, and study
monitors providing direction on a variety of issues. Plan and
manage site visits including accurate chart information, adverse
event reports, information for data queries, and information for
internal and/or external audits as required for each study and each
study participant. Coordinating data collection and surveillance
efforts; organizing all program meetings. (30%)
- Coordinate major activities of laboratory/ research. Provide
input and recommendations to the laboratory director and laboratory
manager regarding significant developments in diagnostic and
surveillance projects. Provide input and recommendations about
ongoing diagnostic assays, validations, and works with laboratory
leadership to identify growth in the diagnostic and surveillance
areas for prion disease and other adult neurodegenerative
disorders. Assist in preparing for regulatory inspections from Ohio
State and New York State. Coordinate information with others as
- Perform the high complexity analytical procedures. Utilize new
and innovative research techniques involving a high degree of skill
and training. (20%)
- Assist in developing procedures; coordinate information with
others as needed. Coordinate major activities of laboratory/
research like standard of procedures for diagnostic testing,
competency of testing personnel in the molecular laboratory.
- May teach or instruct others in research techniques. Train
assigned stakeholders on human subjects' research and ensure all
proper institutional Training / documentation has been received
prior to initiation of work on designated protocols. Teach
postdoctoral scholars/fellows and trainees bio banking /
biorepository best practices. Provide analytical and pre-analytical
training and oversight to laboratory staff. (10%)
- Co-author diagnostic, surveillance, and research projects. May
participate in manuscript and grant writing, co-author test
validation or research projects and independently write progress
reports, manuscripts and tasks related to clinical trials (5%)
- May assist research assistants, technicians, and part-time
students. Support clinical and research staff, including research
associates or testing personnel, students, fellows and residents
and lower-level research staff, assure, all guidelines are followed
by the project staff for each study. (5%)
- Perform other duties as assigned. (
Department: Daily contact with NPDPSC leadership, technical staff,
and administrative staff to discuss diagnostic testing and research
and maintain workflow in the laboratory.
University: Occasional contact with other departments to share
External: Some contact with vendors to exchange information.
Students: Limited or no contact with student employees to exchange
May supervise research assistants and technicians. Train new
laboratory technicians and student employees and occasionally
direct the work of student employees when necessary.
Experience: 5 to 8 years of related experience required.
Education/Licensing: Bachelor's degree in science. ASCP
certification or other clinical specialty like chemistry C(ASCP) or
medical technologists (MLS or MLT) is preferred.
- Must be extremely well organized and capable of setting
priorities while maintaining consistent attention to accuracy and
- Must show great transparency in work and be able to create
SOP's as necessary for work functions and protocols. Must keep
exceptionally accurate and easily retrievable records.
- Has knowledge of commonly-used concepts, practices, and
procedures within the field of prion diseases.
- Must be motivated to explore and learn new laboratory
techniques and must be able to teach laboratory techniques to other
- Ability to work under pressure, multi-task, and be a team
- Punctuality and good attendance required. Ability to meet
- Must be able to manage specimen storage.
- Ability to operate a variety of laboratory equipment.
- Excellent oral and written communication skills and
interpersonal skills; must demonstrate the ability to effectively
and professionally communicate and work with various individuals
from a broad spectrum of disciplines, technical and educational
backgrounds within the department, School and University, and with
individuals outside the university.
- Good/strong organization skills; ability to multi-task,
prioritize and meet deadlines. Must demonstrate attention to detail
and accuracy, time management skills, and follow-through.
- Ability to work with sensitive information and maintain
- Effective problem-solving skills; must demonstrate sound
judgment and good decision-making.
- Must demonstrate compliance with university policies and
procedures guidelines and other applicable regulatory guidelines
(CLIA, NY State CLEP).
- Ability to interact with colleagues, supervisors and customers
face to face.
Standard laboratory conditions with some hazardous chemicals.
Special hazards include biohazardous (potentially infectious) human
brain and cerebrospinal fluid and other bloodborne pathogens and
chemicals. The following personal protective equipment required:
appropriate gloves, protective eyewear, laboratory coat, and safety
This position does not qualify for the Case Western Reserve
University hybrid work program.
In employment, as in education, Case Western Reserve University is
committed to Equal Opportunity and Diversity. Women, veterans,
members of underrepresented minority groups, and individuals with
disabilities are encouraged to apply.
Case Western Reserve University provides reasonable accommodations
to applicants with disabilities. Applicants requiring a reasonable
accommodation for any part of the application and hiring process
should contact the Office of Equity at to request a reasonable
accommodation. Determinations as to granting reasonable
accommodations for any applicant will be made on a case-by-case
Keywords: Case Western Reserve University, Cleveland , Senior Research Assistant, Accounting, Auditing , Bedford, Ohio
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